Retinoblastoma Antibody / Rb1
| Code | Size | Price |
|---|
| NSJ-RQ5141-100ul | 100ul | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: FCD-18
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the Rb1 antibody at -20°C.
Documents
Further Information
Application Details :
Western blot: 1:1000-1:2000
Application Note:
Optimal dilution of the Rb1 antibody should be determined by the researcher.
Description:
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human Retinoblastoma / Rb was used as the immunogen for the Rb1 antibody.
Limitation:
This Rb1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P06400