EIF4E Antibody

NSJ Bioreagents
Product Code: NSJ-RQ5157
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ5157-100ul100ul£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: AFHI-5
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the EIF4E antibody at -20°C.

Images

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Western blot testing of human HEK293 cell lysate with EIF4E antibody. Predicted molecular weight ~27 kDa.

Western blot testing of human HEK293 cell lysate with EIF4E antibody. Predicted molecular weight ~27 kDa.

Further Information

Application Details :
Western blot: 1:100-1:5000
Application Note:
Optimal dilution of the EIF4E antibody should be determined by the researcher.
Description:
eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human EIF4E was used as the immunogen for the EIF4E antibody.
Limitation:
This EIF4E antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P06730