CD3 epsilon Antibody

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NSJ Bioreagents
Product Code: NSJ-RQ5184
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ5184-100ul100ul£535.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: COB-3
Regulatory Status: RUO
Target Species: Mouse
Application: Immunohistochemistry (IHC)
Storage:
Store the CD3e antibody at -20°C.

Images

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IHC staining of FFPE mouse spleen tissue with CD3e antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
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IHC staining of FFPE mouse spleen tissue with CD3e antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:50-1:200
Application Note:
Optimal dilution of the CD3e antibody should be determined by the researcher.
Description:
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to mouse CD3 epsilon / CD3E was used as the immunogen for the CD3e antibody.
Limitation:
This CD3e antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Mouse
Uniprot #:
P07766