PARP1 Antibody

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NSJ Bioreagents
Product Code: NSJ-RQ5290
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ5290-100ul100ul£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: CFD-16
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the PARP antibody at -20°C.

Images

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Western blot testing of human Jurkat cell lysate with PARP antibody. Predicted molecular weight ~116 kDa (full length), ~24 kDa (DNA-binding domain).
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Western blot testing of human Jurkat cell lysate with PARP antibody. Predicted molecular weight ~116 kDa (full length), ~24 kDa (DNA-binding domain).

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Further Information

Application Details :
Western blot: 1:500-1:2000
Application Note:
Optimal dilution of the PARP antibody should be determined by the researcher.
Description:
The PARP1 gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human PARP (auto-modification/catalytic segment) was used as the immunogen for the PARP antibody.
Limitation:
This PARP antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P09874