PARP1 Antibody

NSJ Bioreagents
Product Code: NSJ-RQ5291
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ5291-100ul100ul£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: ABCG-16
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the PARP1 antibody at -20°C.

Images

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Western blot testing of 1) human HeLa cell lysate and 2) lysate from staurosporine-treated human HeLa cells with PARP1 antibody. Predicted molecular weight ~116 kDa (full length), ~89 kDa (auto-modification/catalytic domain).

Western blot testing of 1) human HeLa cell lysate and 2) lysate from staurosporine-treated human HeLa cells with PARP1 antibody. Predicted molecular weight ~116 kDa (full length), ~89 kDa (auto-modification/catalytic domain).

Further Information

Application Details :
Western blot: 1:500-1:1000
Application Note:
Optimal dilution of the PARP1 antibody should be determined by the researcher.
Description:
The PARP1 gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human PARP1 (auto-modification/catalytic domain) was used as the immunogen for the PARP1 antibody.
Limitation:
This PARP1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P09874