IRF1 Antibody
| Code | Size | Price |
|---|
| NSJ-RQ5339-100ul | 100ul | £535.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: DHE-9
Regulatory Status: RUO
Target Species:
- Human
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store the IRF1 antibody at -20°C.
Documents
Further Information
Application Details :
Western blot: 1:500-1:1000,Immunohistochemistry (FFPE): 1:50-1:100
Application Note:
Optimal dilution of the IRF1 antibody should be determined by the researcher.
Description:
The protein encoded by the IRF1 gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human Interferon regulatory factor 1 was used as the immunogen for the IRF1 antibody.
Limitation:
This IRF1 antibody is available for research use only.
Localization:
Nuclear, cytoplasmic
Purity:
Affinity purified
Species Reactivity :
Human, Rat
Uniprot #:
P10914