Artemisinin
| Code | Size | Price |
|---|
| CDX-A0335-M100 | 100 mg | £65.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Arteannuin; Qinghaosu; NSC 369397
Appearance:
White powder.
CAS:
63968-64-9
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS02,GHS09
Handling Advice:
Protect from light and moisture.
Hazards:
H242, H400, H410
InChi:
InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChiKey:
BLUAFEHZUWYNDE-NNWCWBAJSA-N
Long Description:
Chemical. CAS: 63968-64-9. Formula: C15H22O5. MW: 282.33. Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. Artemisinin induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells.
MDL:
MFCD00081057
Molecular Formula:
C15H22O5
Molecular Weight:
282.33
Package Type:
Vial
Precautions:
P210, P220, P234, P273, P280, P370+P378, P391, P403+P235, P411, P420, and P501
Product Description:
Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. Artemisinin induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells.
Purity:
>95% (HPLC)
Signal Word:
Warning
SMILES:
[H][C@](OC([C@@H]([C@@]1(CC[C@H]([C@@]2(CC3)[H])C)[H])C)=O)([C@]12OO4)O[C@]43C
Solubility Chemicals:
Soluble in DMSO (10mg/ml), ethanol (15mg/ml), methanol or choroform (25mg/ml).
Source / Host:
Isolated from plant source.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) A. Zyad, et al.; Phytother. Res. 32, 216 (2018) | (2) E. Konstat-Korzenny, et al.; Med. Sci. 6, E19 (2018) | (3) Y. Zhang, et al.; Nat. Prod. Bioprospect. 8, 303 (2018) | (4) A. Kumari, et al.; Eur. J. Med. Chem. 163, 804 (2019)