5-Hydroxy-L-tryptophan
| Code | Size | Price |
|---|
| CDX-H0160-G001 | 1 g | £35.00 |
Quantity:
| CDX-H0160-G005 | 5 g | £108.00 |
Quantity:
| CDX-H0160-G025 | 25 g | £401.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: n/a
Antibody Clone: n/a
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Oxitriptan; 5-HTP; L-2-Amino-3-(5-hydroxyindolyl)propionic acid; L-5-HTTP; L-5-Hydroxytryptophan
Appearance:
Off-white powder.
CAS:
08/09/4350
Class:
6.1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS06
Handling Advice:
Protect from light and moisture.
Hazards:
H301
InChi:
InChI=1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1
InChiKey:
LDCYZAJDBXYCGN-VIFPVBQESA-N
Long Description:
Chemical. CAS: 4350-09-8. Formula: C11H12N2O3. MW: 220.22. 5-hydroxy-L-Tryptophan (5-HTP), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin. It is used as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid. It is also used as L-aromatic amino acid decarboxylase substrate. When injected systemically in animals, 5-HTP is converted to serotonin and has both peripheral and central nervous system effects. 5-HTP can also be synthesized by gut microbiota and acts as an activator of the aryl hydrocarbon receptor.
MDL:
MFCD00064341
Molecular Formula:
C11H12N2O3
Molecular Weight:
220.22
Package Type:
Vial
PG:
III
Precautions:
P264, P270, P301 + P310 + P330, P405, P501
Product Description:
5-hydroxy-L-Tryptophan (5-HTP), also known as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin. It is used as a dietary supplement for use as an antidepressant, appetite suppressant, and sleep aid. It is also used as L-aromatic amino acid decarboxylase substrate. When injected systemically in animals, 5-HTP is converted to serotonin and has both peripheral and central nervous system effects. 5-HTP can also be synthesized by gut microbiota and acts as an activator of the aryl hydrocarbon receptor.
Purity:
>99% (HPLC)
Signal word:
Danger
SMILES:
OC1=CC=C(NC=C2C[C@H](N)C(O)=O)C2=C1
Solubility Chemicals:
Soluble in water, chloroform or DMSO.
Source / Host:
Isolated from plant source.
Transportation:
Excepted Quantity
UN Nummer:
2811
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) A. Carlsson, et al.; Nature 180, 1200 (1957) | (2) A. Boiardi, et al.; J. Neurol. 225, 41 (1981) | (3) T.C. Birdsall; Altern. Med. Rev. 3, 271 (1998)| (4) A. Martinez, et al.; Curr. Med. Chem. 8, 1077 (2001) | (5) E.H. Turner, et al.; Pharmacol. Ther. 109, 325 (2006) | (6) C.L. Schmid & L.M. Bohn; J. Neurosci. 30, 13513 (2010) | (7) G.V. Sridharan, et al.; Nat. Commun. 5, 5492 (2014) | (8) R. Haberzettl, et al.; Behav. Brain Res. 277, 204 (2015) | (9) J.-A. Mora-Villalobos & A.-P. Zeng; J. Biol. Eng. 12, 3 (2018)