Ketorolac trometamol
| Code | Size | Price |
|---|
| CDX-K0030-G001 | 1 g | £70.00 |
Quantity:
| CDX-K0030-G005 | 5 g | £248.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: n/a
Antibody Clone: n/a
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+20°C
Documents
Further Information
Alternate Names/Synonyms:
(?)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid tris salt; Ketorolac tromethamine; Toradol; Ketorolac tris salt
Appearance:
White to off-white powder.
CAS:
74103-07-4
Class:
6.1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS06
Handling Advice:
Protect from light and moisture.
Hazards:
H301-H315-H319-H335
InChi:
InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2
InChiKey:
BWHLPLXXIDYSNW-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 74103-07-4. Formula: C15H13NO3 . C4H11NO3. MW: 376.4. Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) to treat pain. It is a non-selective COX inhibitor (IC50 = 20nM for both COX-1 and COX-2), thereby decreasing prostaglandins. Ketorolac is a racemic mixture containing the active (S)-ketorolac and inactive (R)-ketorolac enantiomers. Formulations containing ketorolac have been used to manage postoperative pain and as ophthalmic solutions to treat ocular pain and inflammation.
MDL:
MFCD00887595
Molecular Formula:
C15H13NO3 . C4H11NO3
Molecular Weight:
376.4
Package Type:
Vial
PG:
III
Precautions:
P261-P301 + P310-P305 + P351 + P338
Product Description:
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) to treat pain. It is a non-selective COX inhibitor (IC50 = 20nM for both COX-1 and COX-2), thereby decreasing prostaglandins. Ketorolac is a racemic mixture containing the active (S)-ketorolac and inactive (R)-ketorolac enantiomers. Formulations containing ketorolac have been used to manage postoperative pain and as ophthalmic solutions to treat ocular pain and inflammation.
Purity:
>99% (HPLC)
Signal word:
Danger
SMILES:
O=C(C1=CC=CC=C1)C2=CC=C3N2CCC3C(O)=O.OCC(CO)(CO)N
Solubility Chemicals:
Soluble in DMSO, DMF, water or methanol.
Source / Host:
Synthetic.
Transportation:
Excepted Quantity
UN Nummer:
2811
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) K.M. Litvak & G.K. McEvoy; Clin. Pharm. 9, 921 (1990) | (2) M.M. Buckley & R.N. Brogden; Drugs 39, 86 (1990) | (3) Y. Zhang, et al.; J. Pharmacol. Exp. Ther. 283, 1069 (1997) | (4) O. Laneuville, et al.; J. Pharmacol. Exp. Ther. 271, 927 (1994)