Risperidone

Chemodex
Product Code: CDX-R0125
Product Group: Other Biochemicals
Supplier: Chemodex
CodeSizePrice
CDX-R0125-M01010 mg£77.00
Quantity:
CDX-R0125-M05050 mg£304.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: n/a
Antibody Clone: n/a
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+20°C

Images

1 / 1
Chemical Structure

Chemical Structure

Further Information

Alternate Names/Synonyms:
R64766; Apexidone; Psychodal
Appearance:
White to off-white powder.
CAS:
106266-06-2
Class:
6.1
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS06
Handling Advice:
Protect from light and moisture.
Hazards:
H301
InChi:
InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3
InChiKey:
RAPZEAPATHNIPO-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 106266-06-2. Formula: C17H26N2O. MW: 410.48. Risperidone is a benzisoxazole derivative and serotonin-dopamine antagonist. It is an atypical antipsychotic that binds to dopamine D2 receptors (Ki=3nM) and the serotonin (5-HT) receptor subtype 5-HT2A (Ki=0.12nM). It also binds to dopamine D4, ?1- and ?2-adrenergic, 5-HT1C, 5-HT1D, and histamine H1 receptors. It therefore functions as an antagonist for dopamine D2, histamine H1 and alpha1 and alpha2 adrenergic receptors. Formulations containing risperidone have been used in the treatment of schizophrenia, autism and bipolar disorder.
MDL:
MFCD00274576
Molecular Formula:
C17H26N2O
Molecular Weight:
410.48
Package Type:
Vial
PG:
III
Precautions:
P301 + P310
Product Description:
Risperidone is a benzisoxazole derivative and serotonin-dopamine antagonist. It is an atypical antipsychotic that binds to dopamine D2 receptors (Ki=3nM) and the serotonin (5-HT) receptor subtype 5-HT2A (Ki=0.12nM). It also binds to dopamine D4, ?1- and ?2-adrenergic, 5-HT1C, 5-HT1D, and histamine H1 receptors. It therefore functions as an antagonist for dopamine D2, histamine H1 and alpha1 and alpha2 adrenergic receptors. Formulations containing risperidone have been used in the treatment of schizophrenia, autism and bipolar disorder.
Purity:
>98% (HPLC)
Signal word:
Danger
SMILES:
O=C1C(CCN2CCC(C3=NOC4=C3C=CC(F)=C4)CC2)=C(C)N=C5CCCCN51
Solubility Chemicals:
Soluble in DMSO (5mg/ml).
Source / Host:
Synthetic.
Transportation:
Excepted Quantity
UN Nummer:
2811
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.

References

(1) J.E. Leysen, et al.; Mol. Pharmacol. 41, 494 (1992) | (2) F.P. Bymaster, et al.; Neuropsychopharmacol. 14, 87 (1996)