D-(-)-Salicin
| Code | Size | Price |
|---|
| CDX-S0001-G025 | 25 g | £102.00 |
Quantity:
| CDX-S0001-G100 | 100 g | £285.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: n/a
Antibody Clone: n/a
Regulatory Status: RUO
Shipping:
Ambient
Storage:
+20°C
Documents
Further Information
Alternate Names/Synonyms:
D-(-)-Salicin; 2-(Hydroxymethyl)phenyl-beta-D-glucopyranoside; Salicoside; Salicyl alcohol glucoside; Saligenin beta-D-glucoside; NSC 5751
Appearance:
White to off-white powder.
CAS:
138-52-3
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C13H18O7/c14-5-7-3-1-2-4-8(7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
InChiKey:
NGFMICBWJRZIBI-UJPOAAIJSA-N
Long Description:
Chemical. CAS: 138-52-3. Formula: C13H18O7. MW: 286.28. Salicin is an alcoholic beta-glucoside derived from willow bark that produces antioxidant and anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin. It acts as a non-selective COX inhibitor for COX-1 and COX-2. It has been used in the treatment of rheumatism. Shown to inhibit angiogenesis by blocking the ROS-ERK pathways and to have in vivo anticancer activity.
MDL:
MFCD00006590
Molecular Formula:
C13H18O7
Molecular Weight:
286.28
Package Type:
Vial
Product Description:
Salicin is an alcoholic beta-glucoside derived from willow bark that produces antioxidant and anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin. It acts as a non-selective COX inhibitor for COX-1 and COX-2. It has been used in the treatment of rheumatism. Shown to inhibit angiogenesis by blocking the ROS-ERK pathways and to have in vivo anticancer activity.
Purity:
>99% (HPLC)
SMILES:
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC=CC=C2CO)O1
Solubility Chemicals:
Soluble in water (10mg/ml), DMSO (20mg/ml) or DMF (30mg/ml).
Source / Host:
Isolated from plant source.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.
References
(1) T. Maclagan; Br. Med. J. 1, 627 (1876) | (2) T.D. Warner, et al.; PNAS 96, 7563 (1999) | (3) I. Wagner & L. Heide; J. Rheumatol. 30, 1125 (2003) | (4) A.L. Blobaum & L.J. Marnett; J. Med. Chem. 50, 1425 (2007) | (5) N. Verma, et al.; Inflamm. Res. 63, 161 (2014) | (6) C.S. Kong, et al.; Phytother. Res. 28, 1246 (2014) | (7) Y. Li, et al.; Int. Immunopharmacol. 26, 286 (2015) | (8) M. Sabaa, et al.; Naunyn Schmiedebergs Arch. Pharmacol. 390, 1061 (2017)