BIRC3 Antibody

ProSci
Product Code: PSI-13-293
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-13-293-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of U-937 cells, using BIRC3 antibody (13-293).<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
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Immunofluorescence analysis of U2OS cells using BIRC3 antibody (13-293) at dilution of 1:100. Blue: DAPI for nuclear staining.

Western blot analysis of extracts of U-937 cells, using BIRC3 antibody (13-293).<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunofluorescence analysis of U2OS cells using BIRC3 antibody (13-293) at dilution of 1:100. Blue: DAPI for nuclear staining.

Further Information

Additional Names:
BIRC3, TNFR2-TRAF signaling complex protein, RNF49, MIHC, MALT2, HIAP1, HAIP1, c-IAP2, CIAP2, baculoviral IAP repeat-containing protein 3, baculoviral IAP repeat-containing 3, apoptosis inhibitor 2, API2, AIP1, IAP1
Application Note:
WB: 1:200 - 1:2000

IF: 1:50 - 1:200
Background:
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BIRC3 (NP_001156.1).
NCBI Gene ID #:
330
NCBI Official Name:
baculoviral IAP repeat containing 3
NCBI Official Symbol:
BIRC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 68kDa
Purification:
Affinity purification
Research Area:
Apoptosis, Cancer, Cell Cycle, Immunology
Swissprot #:
Q13489
User NOte:
Optimal dilutions for each application to be determined by the researcher.