SCN7A Antibody
| Code | Size | Price |
|---|
| PSI-13-423-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
NaG, Nav2.1, Nav2.2, SCN6A, sodium channel protein type 7 subunit alpha, putative voltage-gated sodium channel subunit alpha Nax, sodium channel protein cardiac and skeletal muscle subunit alpha, sodium channel protein type VII subunit alpha, sodium channel, voltage-gated, type VI, alpha polypeptide, sodium channel, voltage-gated, type VII, alpha subunit, voltage-dependent sodium channel alpha subunit
Application Note:
WB: 1:500 - 1:2000
Background:
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 265-368 of human SCN7A (NP_002967.2).
NCBI Gene ID #:
6332
NCBI Official Name:
sodium voltage-gated channel alpha subunit 7
NCBI Official Symbol:
SCN7A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 260kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q01118
User NOte:
Optimal dilutions for each application to be determined by the researcher.