MED23 Antibody
| Code | Size | Price |
|---|
| PSI-13-476-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
ARC13CRSP13CRSP133, CRSP3, DRIP13MRT18, SUR-2, SUR2, mediator of RNA polymerase II transcription subunit 23, 130 kDa transcriptional co-activator, 133 kDa transcriptional co-activator, activator-recruited cofactor 130 kDa component, cofactor required for Sp1 transcriptional activation subunit 3, vitamin D3 receptor interacting protein
Application Note:
WB: 1:500 - 1:2000
Background:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 890-1110 of human MED23 (NP_001257450.1).
NCBI Gene ID #:
9439
NCBI Official Name:
mediator complex subunit 23
NCBI Official Symbol:
MED23
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 170kDa
Purification:
Affinity purification
Research Area:
Signal Transduction
Swissprot #:
Q9ULK4
User NOte:
Optimal dilutions for each application to be determined by the researcher.