IARS Antibody
| Code | Size | Price |
|---|
| PSI-13-488-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
GRIDHH1, ILERS, ILRS, IRS, PRO0785, IARS, isoleucine--tRNA ligase, cytoplasmic, isoleucine tRNA ligase 1, cytoplasmic
Application Note:
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IHC: 1:50 - 1:100
Background:
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1158-1262 of human IARS (NP_002152.2).
NCBI Gene ID #:
3376
NCBI Official Name:
isoleucyl-tRNA synthetase
NCBI Official Symbol:
IARS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 144kDa
Purification:
Affinity purification
Research Area:
Other
Swissprot #:
P41252
User NOte:
Optimal dilutions for each application to be determined by the researcher.