KCNMB2 Antibody

ProSci
Product Code: PSI-13-551
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-13-551-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using KCNMB2 antibody (13-551) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
2 / 2
Immunohistochemistry of paraffin-embedded human appendix using KCNMB2 antibody (13-551) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using KCNMB2 antibody (13-551) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
Immunohistochemistry of paraffin-embedded human appendix using KCNMB2 antibody (13-551) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
calcium-activated potassium channel subunit beta-2, BK channel beta subunit 2, BK channel subunit beta-2, MaxiK channel beta 2 subunit, MaxiK channel beta-subunit 2, big potassium channel beta subunit 2, charybdotoxin receptor subunit beta-2, hCG1646471, hbeta2, k(VCA)beta-2, large conductance calcium-activated potassium channel beta 2 subunit, large-conductance Ca2+-activated K+ channel beta2 subunit, potassium channel subfamily M regulatory beta subunit 2, potassium large conductance calcium-activated channel, subfamily M, beta member 2, slo-beta-2
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants of this gene. Additional variants are discussed in the literature, but their full length nature has not been described.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 68-194 of human KCNMB2 (NP_005823.1).
NCBI Gene ID #:
10242
NCBI Official Name:
potassium calcium-activated channel subfamily M regulatory beta subunit 2
NCBI Official Symbol:
KCNMB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 30kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q9Y691
User NOte:
Optimal dilutions for each application to be determined by the researcher.