RAC2 Antibody

ProSci
Product Code: PSI-14-009
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-14-009-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of HL-60 cells, using RAC2 antibody (14-009) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded rat brain using RAC2 antibody (14-009) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophagus using RAC2 antibody (14-009) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse stomach using RAC2 antibody (14-009) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of HL-60 cells, using RAC2 antibody (14-009) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded rat brain using RAC2 antibody (14-009) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using RAC2 antibody (14-009) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse stomach using RAC2 antibody (14-009) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
RAC2, ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2), EN-7, Ras-related C3 botulinum toxin substrate 2, rho family, small GTP binding protein Rac2, Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-, Gx, HSPC022, p21-Rac2
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100

IF: 1:50 - 1:100
Background:
This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-192 of human RAC2 (NP_002863.1).
NCBI Gene ID #:
5880
NCBI Official Name:
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
NCBI Official Symbol:
RAC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 21kDa
Purification:
Affinity purification
Research Area:
Cell Cycle, Immunology, Signal Transduction
Swissprot #:
P15153
User NOte:
Optimal dilutions for each application to be determined by the researcher.