TARDBP Antibody
| Code | Size | Price |
|---|
| PSI-14-156-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
TDP43 Antibody: ALS10, TDP-43, TDP43, TAR DNA-binding protein 43
Application Note:
WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
IF: 1:20 - 1:100
IP: 1:50 - 1:100
RIP: 1:20 - 1:50
IHC: 1:50 - 1:100
IF: 1:20 - 1:100
IP: 1:50 - 1:100
RIP: 1:20 - 1:50
Background:
HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human TARDBP (NP_031401.1).
NCBI Gene ID #:
23435
NCBI Official Name:
TAR DNA binding protein
NCBI Official Symbol:
TARDBP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 42kDa
Purification:
Affinity purification
Research Area:
Apoptosis, Cell Cycle, Neuroscience
Swissprot #:
Q13148
User NOte:
Optimal dilutions for each application to be determined by the researcher.