ALDH18A1 Antibody
| Code | Size | Price |
|---|
| PSI-14-332-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
ALDH18A1, pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase), PYCS, P5CS, MGC117316, GSAS, delta1-pyrroline-5-carboxlate synthetase, aldehyde dehydrogenase 18A1, aldehyde dehydrogenase 18 family, member A1
Application Note:
WB: 1:500 - 1:2000
Background:
This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ALDH18A1 (NP_002851.2).
NCBI Gene ID #:
5832
NCBI Official Name:
aldehyde dehydrogenase 18 family, member A1
NCBI Official Symbol:
ALDH18A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 87kDa
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
P54886
User NOte:
Optimal dilutions for each application to be determined by the researcher.