C1 Inactivator Antibody

ProSci
Product Code: PSI-14-404
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-14-404-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of mouse heart, using C1 Inactivator Antibody (14-404) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded rat kidney using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human breast cancer using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse liver using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of mouse heart, using C1 Inactivator Antibody (14-404) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded rat kidney using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human breast cancer using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse liver using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using C1 Inactivator antibody (14-404) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
SERPING1, C1-inhibiting factor, C1IN, C1 Inh, C1-INH, C1INH, C1NH, C1 Inhibitor, HAE1, HAE2, Plasma protease C1 inhibitor, C1 esterase inhibitor, Serpin G1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-500 of human C1 Inactivator (NP_001027466.1).
NCBI Gene ID #:
710
NCBI Official Name:
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
NCBI Official Symbol:
SERPING1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 60kDa
Purification:
Affinity purification
Research Area:
Immunology, Innate Immunity
Swissprot #:
P05155
User NOte:
Optimal dilutions for each application to be determined by the researcher.