S100A12 Antibody

ProSci
Product Code: PSI-14-463
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-14-463-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded human esophagus using S100A12 antibody (14-463) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human gastric cancer using S100A12 antibody (14-463) at dilution of 1:100 (40x lens).

Immunohistochemistry of paraffin-embedded human esophagus using S100A12 antibody (14-463) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using S100A12 antibody (14-463) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
CAAF1, CAGC, CGRP, ENRAGE, MRP-6, MRP6, p6, protein S100-A12, EN-RAGE, calcitermin, calcium-binding protein in amniotic fluid 1, calgranulin C, extracellular newly identified RAGE-binding protein, migration inhibitory factor-related protein 6, neutrophil S100 protein
Application Note:
IHC: 1:50 - 1:100
Background:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A12 (NP_005612.1).
NCBI Gene ID #:
6283
NCBI Official Name:
S100 calcium binding protein A12
NCBI Official Symbol:
S100A12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Chemokines & Cytokines, Immunology, Innate Immunity, Neuroscience, Signal Transduction
Swissprot #:
P80511
User NOte:
Optimal dilutions for each application to be determined by the researcher.