VEGFB Antibody

ProSci
Product Code: PSI-14-581
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-14-581-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western blot analysis of extracts of U-87MG cells, using VEGFB antibody (14-581) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 90s.
2 / 2
Immunohistochemistry of paraffin-embedded human mammary cancer using VEGFB antibody (14-581) at dilution of 1:200 (40x lens).

Western blot analysis of extracts of U-87MG cells, using VEGFB antibody (14-581) at 1:3000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human mammary cancer using VEGFB antibody (14-581) at dilution of 1:200 (40x lens).

Further Information

Additional Names:
Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF, VEGFB, VRF
Application Note:
WB: 1:1000 - 1:2000

IHC: 1:50 - 1:200

IF: 1:50 - 1:200
Background:
This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 25-207 of human VEGFB (NP_003368.1).
NCBI Gene ID #:
7423
NCBI Official Name:
Vascular endothelial growth factor B
NCBI Official Symbol:
VEGFB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 21kDa
Purification:
Affinity purification
Research Area:
Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Neuroscience, Signal Transduction
Swissprot #:
P49765
User NOte:
Optimal dilutions for each application to be determined by the researcher.