Further Information
CDC2L1, CDK11, CDK11-p11CDK11-p46, CDK11-p58, CLK-1, PITSLREA, PK58, p58, p58CDC2L1, p58CLK-1, cyclin-dependent kinase 11B, CDC-related protein kinase p58, PITSLRE serine/threonine-protein kinase CDC2L1, cell division cycle 2-like 1 (PITSLRE proteins), cell division protein kinase 11B, galactosyltransferase-associated protein kinase p58/GTA, p58 CLK-1
WB: 1:500 - 1:2000
IF: 1:50 - 1:200
This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human CDK11B (NP_277021.2).
984
cyclin dependent kinase 11B
CDK11B
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 110kDa
Affinity purification
Apoptosis, Cancer, Cell Cycle, Signal Transduction
P21127
Optimal dilutions for each application to be determined by the researcher.