CEL Antibody

ProSci
Product Code: PSI-14-743
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-14-743-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of mouse pancreas, using CEL antibody (14-743) at 1:3000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

Western blot analysis of extracts of mouse pancreas, using CEL antibody (14-743) at 1:3000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

Further Information

Additional Names:
BAL, BSDL, BSSLL, CEase, FAP, FAPP, LIPA, MODY8, CEL, bile salt-activated lipase, bile salt-dependent lipase, oncofetal isoform, bucelipase, carboxyl ester hydrolase, carboxyl ester lipase (bile salt-stimulated lipase), cholesterol esterase, fetoacinar pancreatic protein, lysophospholipase, pancreatic, sterol esterase
Application Note:
WB: 1:500 - 1:2000
Background:
The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-550 of human CEL (NP_001798.2).
NCBI Gene ID #:
1056
NCBI Official Name:
carboxyl ester lipase
NCBI Official Symbol:
CEL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 67kDa
Purification:
Affinity purification
Research Area:
Cancer, Cell Cycle
Swissprot #:
P19835
User NOte:
Optimal dilutions for each application to be determined by the researcher.