TONSL Antibody
| Code | Size | Price |
|---|
| PSI-14-758-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
NFKBIL2, FLJ40087, IKBR, NFKBIL2
Application Note:
WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
IHC: 1:100 - 1:200
Background:
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-390 of human TONSL (NP_038460.4).
NCBI Gene ID #:
4796
NCBI Official Name:
tonsoku-like, DNA repair protein
NCBI Official Symbol:
TONSL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 151kDa
Purification:
Affinity purification
Research Area:
Signal Transduction, Transcription
Swissprot #:
Q96HA7
User NOte:
Optimal dilutions for each application to be determined by the researcher.