CRY2 Antibody

ProSci
Product Code: PSI-14-890
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-14-890-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of HeLa cells using CRY2 antibody (14-890).

Immunofluorescence analysis of HeLa cells using CRY2 antibody (14-890).

Further Information

Additional Names:
CRY2, Cryptochrome-2, KIAA0658, Growth-inhibiting protein 37, Photolyase-like 2, PHLL2, HCRY2
Application Note:
WB: 1:500 - 1:2000

IF: 1:50 - 1:200
Background:
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 455-614 of human CRY2 (NP_066940.2).
NCBI Gene ID #:
1408
NCBI Official Name:
cryptochrome circadian clock 2
NCBI Official Symbol:
CRY2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q49AN0
User NOte:
Optimal dilutions for each application to be determined by the researcher.