PICK1 Antibody

ProSci
Product Code: PSI-15-078
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-078-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 5
Immunohistochemistry of paraffin-embedded human colon using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
2 / 5
Immunohistochemistry of paraffin-embedded human prostate using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
3 / 5
Immunohistochemistry of paraffin-embedded human prostate cancer using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
4 / 5
Immunohistochemistry of paraffin-embedded human gastric cancer using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
5 / 5
Immunofluorescence analysis of HeLa cells using PICK1 antibody (15-078). Blue: DAPI for nuclear staining.

Immunohistochemistry of paraffin-embedded human colon using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate cancer using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human gastric cancer using PICK1 antibody (15-078) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of HeLa cells using PICK1 antibody (15-078). Blue: DAPI for nuclear staining.

Further Information

Additional Names:
PICK1, protein interacting with PRKCA 1, MGC15204, PRKCABP, OTTHUMP00000028509, PRKCA-binding protein, protein interacting with C kinase 1, protein kinase C, alpha binding protein
Application Note:
IHC: 1:50 - 1:200

IF: 1:50 - 1:200
Background:
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 260-360 of human PICK1 (NP_036539.1).
NCBI Gene ID #:
9463
NCBI Official Name:
protein interacting with PRKCA 1
NCBI Official Symbol:
PICK1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Neuroscience, Signal Transduction
Swissprot #:
Q9NRD5
User NOte:
Optimal dilutions for each application to be determined by the researcher.