Eif2ak2 Antibody

ProSci
Product Code: PSI-15-086
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-086-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded rat brain using Eif2ak2 antibody (15-086) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded human lung cancer using Eif2ak2 antibody (15-086) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver cancer using Eif2ak2 antibody (15-086) at dilution of 1:200 (40x lens).

Immunohistochemistry of paraffin-embedded rat brain using Eif2ak2 antibody (15-086) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human lung cancer using Eif2ak2 antibody (15-086) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human liver cancer using Eif2ak2 antibody (15-086) at dilution of 1:200 (40x lens).

Further Information

Additional Names:
2310047A08Rik, 4732414G15Rik, AI467567, AI747578, Pkr, Prkr, Tik, interferon-induced, double-stranded RNA-activated protein kinase, IFN- type I-induced and dsRNA-activated kinase, IFN-induced and double-stranded RNA-activated kinase, P1/eIF-2A protein kinase, T-cell viral integration site, dsRNA-activated kinase, eIF-2 alpha, eIF-2A protein kinase 2, interferon-inducible RNA-dependent protein kinase, p68 kinase, protein kinase R, protein kinase RNA-activated, protein kinase, interferon-inducible double stranded RNA dependent, serine/threonine-protein kinase TIK, tyrosine-protein kinase EIF2AK2
Application Note:
IHC: 1:50 - 1:200
Background:
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant protein of mouse Eif2ak2
NCBI Gene ID #:
19106
NCBI Official Name:
eukaryotic translation initiation factor 2-alpha kinase 2
NCBI Official Symbol:
Eif2ak2
NCBI Organism:
Mus musculus
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Apoptosis, Autophagy, Cell Cycle, Immunology, Signal Transduction
User NOte:
Optimal dilutions for each application to be determined by the researcher.