Mitofusin 2 Antibody

ProSci
Product Code: PSI-15-100
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-100-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using Mitofusin 2 Antibody (15-100) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
2 / 4
Immunohistochemistry of paraffin-embedded mouse liver using Mitofusin 2 antibody (15-100) (40x lens).
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Immunohistochemistry of paraffin-embedded human liver damage using Mitofusin 2 antibody (15-100) (40x lens).
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Immunohistochemistry of paraffin-embedded human esophagus using Mitofusin 2 antibody (15-100) (40x lens).

Western blot analysis of extracts of various cell lines, using Mitofusin 2 Antibody (15-100) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
Immunohistochemistry of paraffin-embedded mouse liver using Mitofusin 2 antibody (15-100) (40x lens).
Immunohistochemistry of paraffin-embedded human liver damage using Mitofusin 2 antibody (15-100) (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using Mitofusin 2 antibody (15-100) (40x lens).

Further Information

Additional Names:
D630023P19Rik, Fzo, mitofusin-2, HSG protein, hypertension related protein 1, mitochondrial assembly regulatory factor, transmembrane GTPase MFN2
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 687-757 of mouse Mitofusin 2 (NP_573464.2).
NCBI Gene ID #:
170731
NCBI Official Name:
mitofusin 2
NCBI Official Symbol:
MFN2
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 86kDa
Purification:
Affinity purification
Research Area:
Apoptosis, Autophagy, Cancer, Cell Cycle, Neuroscience, Signal Transduction
User NOte:
Optimal dilutions for each application to be determined by the researcher.