CPA6 Antibody

ProSci
Product Code: PSI-15-125
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-125-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using CPA6 antibody (15-125) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat brain using CPA6 antibody (15-125) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver using CPA6 antibody (15-125) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using CPA6 antibody (15-125) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using CPA6 antibody (15-125) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded rat brain using CPA6 antibody (15-125) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver using CPA6 antibody (15-125) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using CPA6 antibody (15-125) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
Carboxypeptidase A6, 3417-, CPA6, CPAH
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

IF: 1:50 - 1:200
Background:
The gene encodes a member of the peptidase M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature enzyme, which catalyzes the release of large hydrophobic C-terminal amino acids. This enzyme has functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Mutations in this gene may be linked to epilepsy and febrile seizures, and a translocation t(6;8)(q26;q13) involving this gene has been associated with Duane retraction syndrome.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-437 of human CPA6 (NP_065094.3).
NCBI Gene ID #:
57094
NCBI Official Name:
Carboxypeptidase A6
NCBI Official Symbol:
CPA6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 51kDa
Purification:
Affinity purification
Research Area:
Cancer, Cell Cycle, Neuroscience, Signal Transduction
Swissprot #:
Q8N4T0
User NOte:
Optimal dilutions for each application to be determined by the researcher.