IDH3G Antibody
| Code | Size | Price |
|---|
| PSI-15-182-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
isocitric dehydrogenase subunit gamma, isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit, isocitrate dehydrogenase [NAD] subunit gamma, OTTHUMP00000025988, OTTHUMP00000025987, OTTHUMP00000025984, NAD+-specific ICDH, NAD(+)-specific ICDH subunit gamma, NAD (H)-specific isocitrate dehydrogenase gamma subunit, IDH-gamma, H-IDHG, isocitrate dehydrogenase 3 (NAD+) gamma, IDH3G
Application Note:
WB: 1:500 - 1:2000
Background:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 40-170 of human IDH3G (NP_004126.1).
NCBI Gene ID #:
3421
NCBI Official Name:
isocitrate dehydrogenase 3 (NAD+) gamma
NCBI Official Symbol:
IDH3G
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 43kDa
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
P51553
User NOte:
Optimal dilutions for each application to be determined by the researcher.