P2RY2 Antibody

ProSci
Product Code: PSI-15-267
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-267-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using P2RY2 antibody (15-267) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded rat testis using P2RY2 antibody (15-267) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat heart using P2RY2 antibody (15-267) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using P2RY2 antibody (15-267) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded rat testis using P2RY2 antibody (15-267) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using P2RY2 antibody (15-267) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
P2Y purinoceptor 2, P2Y2, ATP receptor, P2U purinoceptor 1, P2U1, P2U receptor 1, Purinergic receptor, P2RY2, P2RU1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 278-377 of human P2RY2 (NP_788086.1).
NCBI Gene ID #:
5029
NCBI Official Name:
P2Y purinoceptor 2
NCBI Official Symbol:
P2RY2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 42-52kDa
Purification:
Affinity purification
Research Area:
Neuroscience, Signal Transduction
Swissprot #:
P41231
User NOte:
Optimal dilutions for each application to be determined by the researcher.