HYAL3 Antibody

ProSci
Product Code: PSI-15-358
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-358-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of U2OS cells using HYAL3 antibody (15-358). Blue: DAPI for nuclear staining.

Immunofluorescence analysis of U2OS cells using HYAL3 antibody (15-358). Blue: DAPI for nuclear staining.

Further Information

Additional Names:
HYAL-3, LUCA-3, LUCA3, hyaluronidase-3, hyaluronoglucosaminidase 3, lung carcinoma protein 3
Application Note:
IF: 1:50 - 1:100
Background:
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 198-417 of human HYAL3 (NP_003540.2).
NCBI Gene ID #:
8372
NCBI Official Name:
hyaluronidase 3
NCBI Official Symbol:
HYAL3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Cancer, Cell Cycle, Signal Transduction
Swissprot #:
O43820
User NOte:
Optimal dilutions for each application to be determined by the researcher.