CNR1 Antibody

ProSci
Product Code: PSI-15-560
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-560-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of NIH3T3 cells, using CNR1 antibody (15-560) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 60s.
2 / 5
Immunohistochemistry of paraffin-embedded human lung cancer using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).
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Immunohistochemistry of paraffin-embedded human stomach cancer using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).
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Immunohistochemistry of paraffin-embedded rat ovary using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).

Western blot analysis of extracts of NIH3T3 cells, using CNR1 antibody (15-560) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 60s.
Immunohistochemistry of paraffin-embedded human lung cancer using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach cancer using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded rat ovary using CNR1 antibody (15-560) at dilution of 1:150 (40x lens).

Further Information

Additional Names:
central cannabinoid receptor, cannabinoid receptor 1, CNR, CB1R, CB1K5, CB1A, CB1, CB-R, CANN6, cannabinoid receptor 1 (brain), CNR1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human CNR1 (NP_001153731.1).
NCBI Gene ID #:
1268
NCBI Official Name:
cannabinoid receptor 1 (brain)
NCBI Official Symbol:
CNR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 53kDa
Purification:
Affinity purification
Research Area:
Cancer, Neuroscience
Swissprot #:
P21554
User NOte:
Optimal dilutions for each application to be determined by the researcher.