HTRA2 Antibody

ProSci
Product Code: PSI-15-773
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-773-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug HTRA2 antibody (15-773). Western blot was performed from the immunoprecipitate using HTRA2 antibody (15-773) at a dilition of 1:1000.

Immunoprecipitation analysis of 200ug extracts of MCF-7 cells, using 3 ug HTRA2 antibody (15-773). Western blot was performed from the immunoprecipitate using HTRA2 antibody (15-773) at a dilition of 1:1000.

Further Information

Additional Names:
OMI Antibody: OMI, PARK13, PRSS25, OMI, Serine protease HTRA2, mitochondrial, High temperature requirement protein A2, HtrA2
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

IP: 1:50 - 1:100
Background:
This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 334-458 of human HTRA2 (NP_037379.1).
NCBI Gene ID #:
27429
NCBI Official Name:
HtrA serine peptidase 2
NCBI Official Symbol:
HTRA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Apoptosis, Cancer, Cell Cycle, Neuroscience
Swissprot #:
O43464
User NOte:
Optimal dilutions for each application to be determined by the researcher.