IVD Antibody

ProSci
Product Code: PSI-15-959
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-15-959-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using IVD antibody (15-959) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 1S.

Western blot analysis of extracts of various cell lines, using IVD antibody (15-959) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 1S.

Further Information

Additional Names:
ACAD2, isovaleryl-CoA dehydrogenase, mitochondrial, epididymis secretory sperm binding protein, isovaleryl Coenzyme A dehydrogenase
Application Note:
WB: 1:200 - 1:2000

IHC: 1:50 - 1:200
Background:
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-200 of human IVD (NP_002216.2).
NCBI Gene ID #:
3712
NCBI Official Name:
isovaleryl-CoA dehydrogenase
NCBI Official Symbol:
IVD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 42kDa
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
P26440
User NOte:
Optimal dilutions for each application to be determined by the researcher.