BMP2 Antibody

ProSci
Product Code: PSI-16-158
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-16-158-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded rat ovary using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat heart using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse liver using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
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Immunofluorescence analysis of U2OS cells using BMP2 antibody (16-158) at dilution of 1:100. Blue: DAPI for nuclear staining.

Immunohistochemistry of paraffin-embedded rat ovary using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse liver using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using BMP2 antibody (16-158) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using BMP2 antibody (16-158) at dilution of 1:100. Blue: DAPI for nuclear staining.

Further Information

Additional Names:
BMP2, BDA2, BMP-2, BMP-2A, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

IF: 1:50 - 1:200
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).
NCBI Gene ID #:
650
NCBI Official Name:
bone morphogenetic protein 2
NCBI Official Symbol:
BMP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Cancer, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Neuroscience, Signal Transduction, Stem Cell
Swissprot #:
P12643
User NOte:
Optimal dilutions for each application to be determined by the researcher.