Factor IX / F9 Antibody

Coagulation factor IX, Christmas factor, Plasma thromboplastin component, PTC, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain, F9

WB: 1:500 - 1:2000

IF: 1:50 - 1:200

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

batch dependent

Unconjugated

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Recombinant fusion protein containing a sequence corresponding to amino acids 29-192 of human Factor IX / F9 (NP_000124.1).

2158

Coagulation factor IX

F9

Homo sapiens

Liquid

Observed: 50kDa

Affinity purification

Immunology, Innate Immunity

P00740

Optimal dilutions for each application to be determined by the researcher.