HSCB Antibody
| Code | Size | Price |
|---|
| PSI-16-347-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
DNAJC2HSC2JAC1, iron-sulfur cluster co-chaperone protein HscB, DnaJ (Hsp40) homolog, subfamily C, member 2HscB iron-sulfur cluster co-chaperone homolog, HscB mitochondrial iron-sulfur cluster co-chaperone, J-type co-chaperone HSC2epididymis secretory sperm binding protein, iron-sulfur cluster co-chaperone protein HscB, mitochondrial
Application Note:
WB: 1:500 - 1:2000
Background:
This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human HSCB (NP_741999.3).
NCBI Gene ID #:
150274
NCBI Official Name:
HscB mitochondrial iron-sulfur cluster cochaperone
NCBI Official Symbol:
HSCB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 27kDa
Purification:
Affinity purification
Research Area:
Signal Transduction
Swissprot #:
Q8IWL3
User NOte:
Optimal dilutions for each application to be determined by the researcher.