DiMethyl-DNMT3A-K44 pAb

ProSci
Product Code: PSI-16-374
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-16-374-50uL50uL£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of U2OS cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.
2 / 4
Immunofluorescence analysis of C6 cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.
3 / 4
Immunofluorescence analysis of HeLa cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.
4 / 4
Immunofluorescence analysis of NIH/3T3 cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.

Immunofluorescence analysis of U2OS cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of HeLa cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of NIH/3T3 cells using DiMethyl-DNMT3A-K44 antibody (16-374) at dilution of 1:100. Blue: DAPI for nuclear staining.

Further Information

Additional Names:
MmuIIIA, DNA (cytosine-5)-methyltransferase 3A, DNA MTase MmuIIIA, DNA methyltransferase MmuIIIA
Application Note:
IF: 1:50 - 1:200
Background:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1).
Modifications:
Methylated
NCBI Gene ID #:
13435
NCBI Official Name:
DNA methyltransferase 3A
NCBI Official Symbol:
DNMT3A K44me2
NCBI Organism:
Mus musculus
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Other
Swissprot #:
O88508
User NOte:
Optimal dilutions for each application to be determined by the researcher.