DPYD Antibody
| Code | Size | Price |
|---|
| PSI-16-487-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
DHP, DHPDHASE, DPD, dihydropyrimidine dehydrogenase [NADP(+)], dihydrothymine dehydrogenase, dihydrouracil dehydrogenase
Application Note:
WB: 1:500 - 1:2000
Background:
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_001153773.1).
NCBI Gene ID #:
1806
NCBI Official Name:
dihydropyrimidine dehydrogenase
NCBI Official Symbol:
DPYD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 112kDa
Purification:
Affinity purification
Research Area:
Signal Transduction
Swissprot #:
Q12882
User NOte:
Optimal dilutions for each application to be determined by the researcher.