CXCR1 Antibody

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ProSci
Product Code: PSI-16-582
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-16-582-50uL50uL£433.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using CXCR1 antibody (16-582) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 15s.
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Immunohistochemistry of paraffin-embedded rat lung using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human colon using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of various cell lines, using CXCR1 antibody (16-582) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 15s.
Immunohistochemistry of paraffin-embedded rat lung using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse spleen using CXCR1 antibody (16-582) at dilution of 1:100 (40x lens).

Documents

Further Information

Additional Names:
IL8RA, interleukin 8 receptor, alpha, interleukin 8 receptor alpha, IL8RBA, IL8R1, IL-8 receptor type 1, CXCR1, CMKAR1, CKR-1, chemokine (C-X-C motif) receptor 1, CDw128a, CD181, CD128, C-C-CKR-1, C-C, IL8RA
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human CXCR1 (NP_000625.1).
NCBI Gene ID #:
3577
NCBI Official Name:
chemokine (C-X-C motif) receptor 1
NCBI Official Symbol:
CXCR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 70kDa
Purification:
Affinity purification
Research Area:
Cancer, Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction
Swissprot #:
P25024
User NOte:
Optimal dilutions for each application to be determined by the researcher.