OLR1 Antibody

ProSci
Product Code: PSI-16-584
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-16-584-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 4
Western blot analysis of extracts of various cell lines, using OLR1 antibody (16-584) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
2 / 4
Immunohistochemistry of paraffin-embedded rat brain using OLR1 Antibody (16-584) at dilution of 1:200 (40x lens).
3 / 4
Immunohistochemistry of paraffin-embedded human kidney using OLR1 Antibody (16-584) at dilution of 1:200 (40x lens).
4 / 4
Immunohistochemistry of paraffin-embedded mouse intestine using OLR1 Antibody (16-584) at dilution of 1:200 (40x lens).

Western blot analysis of extracts of various cell lines, using OLR1 antibody (16-584) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded rat brain using OLR1 Antibody (16-584) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney using OLR1 Antibody (16-584) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse intestine using OLR1 Antibody (16-584) at dilution of 1:200 (40x lens).

Further Information

Additional Names:
OLR1, CLEC8A, LOX1, SCARE1, LOXIN, SLOX1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 58-273 of human OLR1 (NP_002534.1).
NCBI Gene ID #:
4973
NCBI Official Name:
oxidized low density lipoprotein (lectin-like) receptor 1
NCBI Official Symbol:
OLR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 26kDa
Purification:
Affinity purification
Research Area:
Cancer
Swissprot #:
P78380
User NOte:
Optimal dilutions for each application to be determined by the researcher.