UGT1A10 Antibody
| Code | Size | Price |
|---|
| PSI-16-648-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
GNT1, UDPGT, UGT-1A, UGT-1J, UGT1, UGT1-01, UGT1-1UGT1.1, UGT1.1UGT1A, UGT1A1, UGT1J, hUG-BR1, UDP-glucuronosyltransferase 1-1Bilirubin-specific UDPGT isozyme 1, UDP glucuronosyltransferase 1 family, polypeptide A1UDP glycosyltransferase 1 family, polypeptide A1UDP-glucuronosyltransferase 1-1, UDP-glucuronosyltransferase 1-A, UDP-glucuronosyltransferase 1-J, UDP-glucuronosyltransferase 1A1, UDP-glucuronosyltransferase 1A1UDPGT 1-1, UDPGT 1-10
Application Note:
WB: 1:500 - 1:2000
Background:
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human UGT1A10 (NP_061948.1).
NCBI Gene ID #:
54575
NCBI Official Name:
UDP glucuronosyltransferase family 1 member A10
NCBI Official Symbol:
UGT1A10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 60kDa
Purification:
Affinity purification
Research Area:
Signal Transduction
Swissprot #:
Q9HAW8
User NOte:
Optimal dilutions for each application to be determined by the researcher.