CACNA1B Antibody

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ProSci
Product Code: PSI-16-713
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-16-713-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of U-87MG cells, using CACNA1B antibody (16-713) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 3min.
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Western blot analysis of extracts of U-87MG cells, using CACNA1B antibody (16-713) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 3min.

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Further Information

Additional Names:
BIII, CACNL1A5, CACNN, Cav2.2, DYT23, voltage-dependent N-type calcium channel subunit alpha-1B, Cav2.2 voltage-gated Ca2+ channel, brain calcium channel III, calcium channel alpha12.2 subunit, calcium channel, L type, alpha-1 polypeptide, calcium channel, voltage-dependent, L type, alpha 1B subunit, calcium channel, voltage-dependent, N type, alpha 1B subunit, voltage-gated calcium channel alpha subunit Cav2.2, voltage-gated calcium channel subunit alpha Cav2.2
Application Note:
WB: 1:500 - 1:2000
Background:
The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 2200 to the C-terminus of human CACNA1B (NP_000709.1).
NCBI Gene ID #:
774
NCBI Official Name:
calcium voltage-gated channel subunit alpha1 B
NCBI Official Symbol:
CACNA1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 262kDa
Purification:
Affinity purification
Research Area:
Neuroscience, Signal Transduction
Swissprot #:
Q00975
User NOte:
Optimal dilutions for each application to be determined by the researcher.