NDUFS1 Antibody

ProSci
Product Code: PSI-16-802
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-16-802-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of U2OS cells using NDUFS1 antibody (16-802). Blue: DAPI for nuclear staining.

Immunofluorescence analysis of U2OS cells using NDUFS1 antibody (16-802). Blue: DAPI for nuclear staining.

Further Information

Additional Names:
NDUFS1, PRO1304, OTTHUMP00000206345, NADH-coenzyme Q reductase, NADH dehydrogenase (ubiqui) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase), 75kDa, MGC26839, complex I, mitochondrial respirato, CI-75Kd, CI-75k
Application Note:
WB: 1:500 - 1:2000

IF: 1:50 - 1:200
Background:
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1 (NP_004997.4).
NCBI Gene ID #:
4719
NCBI Official Name:
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NCBI Official Symbol:
NDUFS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Apoptosis, Cancer, Cell Cycle, Neuroscience
Swissprot #:
P28331
User NOte:
Optimal dilutions for each application to be determined by the researcher.