MED1 Antibody
| Code | Size | Price |
|---|
| PSI-16-892-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
CRSP1, CRSP20DRIP205, DRIP23PBP, PPARBP, PPARGBP, RB18A, TRAP22TRIP2, mediator of RNA polymerase II transcription subunit 1, ARC205, PPAR-binding protein, PPARG binding protein, TR-interacting protein 2, TRIP-2, activator-recruited cofactor 205 kDa component, p53 regulatory protein RB18A, peroxisome proliferator-activated receptor-binding protein, thyroid hormone receptor-associated protein complex 220 kDa component, thyroid hormone receptor-associated protein complex component TRAP22thyroid receptor interacting protein 2, vitamin D receptor-interacting protein 230 kD, vitamin D receptor-interacting protein complex component DRIP205
Application Note:
WB: 1:500 - 1:2000
Background:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MED1 (NP_004765.2).
NCBI Gene ID #:
5469
NCBI Official Name:
mediator complex subunit 1
NCBI Official Symbol:
MED1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 160kDa
Purification:
Affinity purification
Research Area:
Cancer
Swissprot #:
Q15648
User NOte:
Optimal dilutions for each application to be determined by the researcher.