CNR2 Antibody

ProSci
Product Code: PSI-18-009
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-18-009-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using CNR2 antibody (18-009) at 1:3000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human breast cancer using CNR2 antibody (18-009) at dilution of 1:150 (40x lens).
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Immunohistochemistry of paraffin-embedded human stomach using CNR2 antibody (18-009) at dilution of 1:150 (40x lens).

Western blot analysis of extracts of various cell lines, using CNR2 antibody (18-009) at 1:3000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human breast cancer using CNR2 antibody (18-009) at dilution of 1:150 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using CNR2 antibody (18-009) at dilution of 1:150 (40x lens).

Further Information

Additional Names:
CNR3, cannabinoid receptor 2 (macrophage), HGNC:2160, CB2, CX5, OTTHUMP00000044841, CB2A, CB2B
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CNR2 (NP_001832.1).
NCBI Gene ID #:
1269
NCBI Official Name:
cannabinoid receptor 2 (macrophage)
NCBI Official Symbol:
CNR2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 45kDa
Purification:
Affinity purification
Research Area:
Neuroscience, Signal Transduction
Swissprot #:
P34972
User NOte:
Optimal dilutions for each application to be determined by the researcher.