GGT1 Antibody

Contact us
ProSci
Product Code: PSI-18-088
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-18-088-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 4
Western blot analysis of extracts of various cell lines, using GGT1 antibody (18-088) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
2 / 4
Immunohistochemistry of paraffin-embedded rat kidney using GGT1 antibody (18-088) at dilution of 1:100 (40x lens).
3 / 4
Immunohistochemistry of paraffin-embedded human breast cancer using GGT1 antibody (18-088) at dilution of 1:100 (40x lens).
4 / 4
Immunohistochemistry of paraffin-embedded mouse kidney using GGT1 antibody (18-088) at dilution of 1:100 (40x lens).
❮❯

Western blot analysis of extracts of various cell lines, using GGT1 antibody (18-088) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded rat kidney using GGT1 antibody (18-088) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human breast cancer using GGT1 antibody (18-088) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using GGT1 antibody (18-088) at dilution of 1:100 (40x lens).

Documents

Further Information

Additional Names:
GGT1, gamma-glutamyltransferase 1, CD224, D22S672, D22S732, GGT, GGT 1, GTG, gamma-glutamyl transpeptidase, gamma-glutamyltranspeptidase 1, glutamyl transpeptidase, glutathione hydrolase 1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 370-569 of human GGT1 (NP_001027537.1).
NCBI Gene ID #:
2678
NCBI Official Name:
gamma-glutamyltransferase 1
NCBI Official Symbol:
GGT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 60-70kDa
Purification:
Affinity purification
Research Area:
Immunology, Signal Transduction
Swissprot #:
P19440
User NOte:
Optimal dilutions for each application to be determined by the researcher.