CYP24A1 Antibody
| Code | Size | Price |
|---|
| PSI-18-238-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
CYP24A1, P450-CC24, MGC126274, MGC126273, cytochrome P450, subfamily XXIV (vitami, family 24, subfamily A, polypeptide 1, cytochrome P450 family 24 subfamily A polypeptide 1, CYP24, CP24, 24-OHase, 1, 25-@dihydroxyvitamin D3 24-hydroxylase
Application Note:
IHC: 1:50 - 1:100
IF: 1:50 - 1:100
IF: 1:50 - 1:100
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 36-448 of human CYP24A1 (NP_001122387.1).
NCBI Gene ID #:
1591
NCBI Official Name:
cytochrome P450, family 24, subfamily A, polypeptide 1
NCBI Official Symbol:
CYP24A1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
Q07973
User NOte:
Optimal dilutions for each application to be determined by the researcher.